VISDB Viral Integration Site DataBase

VIS ID

TVIS10017887

Fusion event

HBV-ZYG11B integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1793

Integrated sequence

CCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAA| |TTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT

Chromosome

chr1

Cytoband

p32.3

Reference genome

Start

End

53292659/52826987 (Hg38)

Location type

3UTR

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-3149 ; hsa-mir-1303 ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-6872-3p ; hsa-mir-483-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-3653-3p ; hsa-mir-377-3p ; hsa-mir-1248 ; hsa-mir-5088-3p ; hsa-mir-216b-3p ; hsa-mir-129-5p ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-4282 ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-651-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-4790-5p ; hsa-mir-4524a-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3615 ; hsa-mir-4315 ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-376a-5p ; hsa-mir-6873-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-520f-5p ; hsa-mir-5096 ; hsa-mir-6773-5p ; hsa-mir-6724-5p ; hsa-mir-197-3p ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-6823-5p ; hsa-mir-4524b-3p ; hsa-mir-5684 ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-6879-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-3622b-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-3145-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-5693 ; hsa-mir-500b-3p ; hsa-mir-3664-5p ; hsa-mir-514a-5p ; hsa-mir-4714-5p ; hsa-mir-200c-5p ; hsa-mir-550a-3p ; hsa-mir-550b-3p ; hsa-mir-8057 ; hsa-mir-924 ; hsa-mir-103b ; hsa-mir-302c-5p ; hsa-mir-3143 ; hsa-mir-4662a-5p ; hsa-mir-4803 ; hsa-mir-552-5p

Nearest miRNA

hsa-mir-12136/Upstream/990585; hsa-mir-101-1/Downstream/1227092;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/100231, chr1-CpG: 110/Downstream/15635

Upstream sequence

ATCAGAAAAGGCTCTTGACCTCTCTGCTATGTTGCAATACATTTCATCAAAATGAACTTGTCACCGCTTCTCGAAATATGAAATTCTCTCTATCCTTCCA

Downstream sequence

CCCAGCATTCAAAGACATCAGAATTTCCACTAGTTCATGGTGTAGCTAAGGCTGCATCGAAAGACAACATAAGGTGGTTTGAGAAAGGTCCTTTAAGATC