OLFM3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017888
Fusion event
HBV-OLFM3 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1747
Integrated sequence
TCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGA| |GGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCAT
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
102429533/101963977 (Hg38)
End
102429533/101963977 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1E
Target gene
OLFM3
miRNAs that regulate target gene
hsa-mir-10b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1682669; hsa-mir-11399/Downstream/5933246;
Nearest TSS
ENST00000473358/Upstream/53823; ENST00000414923/Downstream/32928;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/726788, chr1-CpG: 85/Downstream/1561493
Upstream sequence
GAAGACCCAGCTTTATCTTCCAAGGGTAACAACATTCCCAAGACTCAGAGCTGGAAGGCGGCAAGAGTGGAGCCAGGAGAGACAGATCGCATCCACTCCT
Downstream sequence
GAGGCCGCCTCGAATGTCTCCATTCCCTTCTGGCCTGCCTTCCCCCTCCCTTCAACCCCAAAGACCCAAGAAGACAACAGAGATCAGAGACCACATCCCT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate