VISDB Viral Integration Site DataBase

VIS ID

TVIS10017890

Fusion event

HBV-KCNT2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1699

Integrated sequence

CACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGA| |GGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTC

Chromosome

chr1

Cytoband

q31.3

Reference genome

Start

End

196343210/196374080 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-4775 ; hsa-mir-500a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/3237497; hsa-mir-1182/Downstream/208333;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/3251986, chr1-CpG: 24/Downstream/234498

Upstream sequence

CCACATGCAAACTGATCCTTCTTTTTCCCTTCCTCCTTACGCCCTAGGAAATGTTCTGTGAAGGTCAAGTGTGCAAACAGACATTCCAGAGAGCCTGATC

Downstream sequence

CACATCCAGCAGCAGAGCCCACTTGTGGCTGCAGCTTTATGCCAAATTATATTGCAGACTGAACAGACGTTTATCTATCCCATTTGGCGACGAGGACTCG