VISDB Viral Integration Site DataBase

VIS ID

TVIS10017895

Fusion event

HBV-FREM2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1825

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAAT

Chromosome

chr13

Cytoband

q13.3

Reference genome

Start

End

39338838/38764701 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29c-3p ; hsa-mir-615-3p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-493-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-6888-3p ; hsa-mir-6873-3p ; hsa-mir-3120-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-3664-5p

Nearest miRNA

hsa-mir-2276/Upstream/14602197; hsa-mir-1267/Downstream/899333;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/76539, chr13-CpG: 49/Downstream/272850

Upstream sequence

TAAAAAAGCAGACATCCTGTTAGCTGCAGGTTGATAAACAAACGGGAGAAGTACTTAACAGCAAAGACAGCTTCCATACCTGTTCAGCAAGCTACACTAC

Downstream sequence

ATCCACAGCAAAAGCATGATGAAATCAAGGCCTTGTGCTGTGTCACTCAAACAACCACTCCAGAACCCTGATGCCTTTCTTGGGGTTACTGTTAATGCaa