VISDB Viral Integration Site DataBase

VIS ID

TVIS10017899

Fusion event

HBV-WDR62 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1678

Integrated sequence

GTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGC| |AATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGA

Chromosome

chr19

Cytoband

q13.12

Reference genome

Start

End

36563872/36072970 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-877-3p ; hsa-mir-769-5p ; hsa-mir-542-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-1260b

Nearest miRNA

hsa-mir-10395/Upstream/727343; hsa-let-7e/Downstream/3336653;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/17807, chr19-CpG: 187/Downstream/40487

Upstream sequence

gccaccacacccagcTCCCTGTCCCTATCTTTCCTCACTGTCCAGCCCCTGACCCTGTTTATTCCCTGCCAGCTGAGCCCTGGAGGGCAGATGGAGGAGG

Downstream sequence

AGAGGCTTTTTGATCATGCGTTGGTGAGGCCAAGAAGAGGTGGGACCTGAGATACATGCCTATTATCTTTCTATGCTCAGAGAGAGAGCAGGAGCTTGGG