APOC1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017900
Fusion event
HBV-APOC1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
Polymerase;
Start
1290
Integrated sequence
CGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCT| |TGTTTTGCTCGCAGCCGGTCTGGGGCGAAACTGCTCGGCACCGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTG
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
45422493/44919236 (Hg38)
End
45422493/44919236 (Hg38)
Location type
3UTR
Fragile sites / regions
FRA19A
Target gene
APOC1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10395/Upstream/160515; hsa-let-7e/Downstream/517418;
Nearest TSS
ENST00000633603/Upstream/4367; ENST00000591600/Downstream/23002;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/9893, chr19-CpG: 64/Downstream/35720
Upstream sequence
TCGGCCTCCCACCCCATCTCCCGGGGGGCGGAGACCCGGGAGCCCAGAGGTGCCCCCCCAACCCGCGGGCCCTCCTCTCCCCTCCCCCTCCCCGCAGCCC
Downstream sequence
GAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCCACCAATAAAAATC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate