EHBP1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017901
Fusion event
HBV-EHBP1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1654
Integrated sequence
GTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACA| |TAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATT
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
GRCh37/hg19
Start
62929576/62702441 (Hg38)
End
62929576/62702441 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
EHBP1
miRNAs that regulate target gene
hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1301/Upstream/496524; hsa-mir-10b/Downstream/1638306;
Nearest TSS
ENST00000437798/Upstream/28563; ENST00000467436/Downstream/3211;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/196079, chr2-CpG: 61/Downstream/3019
Upstream sequence
TGGCTTAGTAAAGGAAGACAAATAGATGACAATGAGTGTTGGGTCAGCCATTAGACAGAGCTGCCTAATGAAAAGGAATGTCTGCTAAATCTAAATAACA
Downstream sequence
GGGAGGGTGAGTAGGAGGTACCTGTTGGTTGGTAGGGGAAATGGGACCTTAAGAAAAGGGTAACTTCTAGCATGCCAAAAGTTCTCAGCTAATATATGAC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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