Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017903
Fusion event
HBV-MRPS9 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
core protein;X protein;
Start
1819
Integrated sequence
TATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATA
Host Sequence
Chromosome
chr2
Cytoband
q12.1
Reference genome
End
105716039/105099581 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/2667215; hsa-mir-10b/Downstream/4041909;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/61268, chr2-CpG: 85/Downstream/44275
Upstream sequence
ACCACTCACCTGTTTTCTGTCTTCCTCTAAGAGGTGTGCTCTCATGTTGTTCGTAGACACTGGAGACACTCACTACATATTCTGTACCAGGCAGGAGATC
Downstream sequence
AACAGTACCTATAAATTTATGAACCTGCTTTTCTTCTGGGCAGCATGCATATTAATGGTTCCTAAAGGCTTCTCTTTTTATGCTGCAGCTGGACTACTTA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.