Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017908
Fusion event
HBV-SYS1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1717
Integrated sequence
CCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTG| |TGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGC
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
Start
End
43997498/45368858 (Hg38)
Location type
3UTR
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-103a-2/Upstream/960655; hsa-mir-1-1/Downstream/56652;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/5131, chr20-CpG: 140/Downstream/36960
Upstream sequence
CTGGGCTGGGCAAGCTCCACTGGGAACCGAGGGCCCAGTCAGGCCCTGAGTAGGCAAAAGGAGGACACAGCCAGTGAATGAGAGAGAATGTTCCTTACAG
Downstream sequence
AGCCGTGGTGGTGGTTACTCCATCTGTGGTtggagcgcctctttgggattcacttcaaggtcttgtgcctatttttctgcatatcttctgtgatgacaaa
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.