SYS1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017909
Fusion event
HBV-SYS1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
core protein;X protein;
Start
1830
Integrated sequence
TGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCT| |CTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGA
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
43997507/45368867 (Hg38)
End
43997507/45368867 (Hg38)
Location type
3UTR
Target gene
SYS1
miRNAs that regulate target gene
hsa-mir-103a-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/960664; hsa-mir-1-1/Downstream/56643;
Nearest TSS
ENST00000382410/Upstream/3648; ENST00000372723/Downstream/9526;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/5140, chr20-CpG: 140/Downstream/36951
Upstream sequence
GGCAGCCCGCGGAGACCGAGGCTCCTCTGTGACGTCAGCAGCCGGCCGGGACACAGCGGGAGGGCAGGTGCGGCCGCGGGGCCTGCCGACTTCACGCAGG
Downstream sequence
GGTGGTTACTCCATCTGTGGTtggagcgcctctttgggattcacttcaaggtcttgtgcctatttttctgcatatcttctgtgatgacaaatctctgtcc
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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