VISDB Viral Integration Site DataBase

VIS ID

TVIS10017914

Fusion event

HBV-FGB integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1760

Integrated sequence

GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTA| |AAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCAC

Chromosome

chr4

Cytoband

q31.3

Reference genome

Start

End

155484644/154563492 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-409-3p ; hsa-mir-29c-3p ; hsa-mir-144-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-5096 ; hsa-mir-5587-5p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-197-3p ; hsa-mir-6832-5p ; hsa-mir-6801-5p ; hsa-mir-193b-5p ; hsa-mir-1279 ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-6890-5p

Nearest miRNA

hsa-mir-12113/Upstream/2026976; hsa-mir-1305/Downstream/4565310;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/12962, chr4-CpG: 39/Downstream/63340

Upstream sequence

TCAGTATTCTTTTGGAAAAATTAAATGTACTCTTAGAGGGAAAGCGTTGCAAAACTAGCCTTTAAATATAATTGGCAAAGCATTTTGTTTTGTGAGGGTT

Downstream sequence

AAAGAGCAGAATTTTAAGATAAAAGAAACTGGTGGTAGGTAGATTGTTCTTTGGTGAAGGAAGGTAATATATATTGTTACTGAGATTACTATTTATAAAA