VISDB Viral Integration Site DataBase

VIS ID

TVIS10017915

Fusion event

HBV-MAN2A1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1763

Integrated sequence

TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAG| |GTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGT

Chromosome

chr5

Cytoband

q21.3

Reference genome

Start

End

109144601/109808900 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-188-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-4633-5p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-5697 ; hsa-mir-532-5p ; hsa-mir-4521 ; hsa-mir-219b-5p ; hsa-mir-576-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p

Nearest miRNA

hsa-mir-10397/Upstream/8992335; hsa-mir-103a-1/Downstream/704929;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/117900, chr5-CpG: 24/Downstream/76385

Upstream sequence

AAGCTAGCTTTGTACCCAAATACCTCTCATCCTCTCATTGAAATGaatattaaaaataaataaaatGCTTAAATAATGACCATACTGGTAGCAGTCTCTG

Downstream sequence

ccatgtttgccaggctggtctcgaactccttacctcgggtgatctgcctgcctcggcctcccaaagtgctaggattacaggcatgagccaccacatctgg