COMMD10 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017916
Fusion event
HBV-COMMD10 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
core protein;Polymerase;
Start
2320
Integrated sequence
TCTTACTTTTGGAAGAGAAACTGTTCTTGAGTATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCCGCTTACAGACCACCAAATGCCCCTATCTTA| |TCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCA
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
115529591/116193894 (Hg38)
End
115529591/116193894 (Hg38)
Location type
Intronic
Target gene
COMMD10
miRNAs that regulate target gene
hsa-mir-16-5p
Nearest miRNA
hsa-mir-10397/Upstream/5679979; hsa-mir-103a-1/Downstream/61849;
Nearest TSS
ENST00000502646/Upstream/102815; ENST00000508250/Downstream/97645;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/108426, chr5-CpG: 45/Downstream/167543
Upstream sequence
TCCCCGCAAACAGCTTGTTCTCCATGTCGCCGTAGCACAGGCTGCAGAGCAGCGTGGAGAGGATGGAGCCCTGCGGGATCCCCTGGCACTGGACGTAGGA
Downstream sequence
gatagaccatataattgaggccataaaatgagcctcaataaatttaagaaaactgaaatgatatcaagccactctctcagaccacagtggaataaaactg
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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