VISDB Viral Integration Site DataBase

VIS ID

TVIS10017918

Fusion event

HBV-COL19A1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1823

Integrated sequence

TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGA

Chromosome

chr6

Cytoband

q13

Reference genome

Start

End

70625077/69915185 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-223-5p ; hsa-mir-126-5p ; hsa-mir-4795-3p ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-496 ; hsa-mir-5571-5p ; hsa-mir-544a ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-3182 ; hsa-mir-676-5p ; hsa-mir-20a-3p ; hsa-mir-6515-3p ; hsa-mir-877-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-330-3p ; hsa-mir-141-5p ; hsa-mir-578 ; hsa-mir-8070 ; hsa-mir-3161 ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-581

Nearest miRNA

hsa-mir-10398/Upstream/12524973; hsa-mir-10524/Downstream/1461775;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/47505, chr6-CpG: 61/Downstream/367152

Upstream sequence

cagcgctttgggaggccgaggcaggcggatcatgaggtcaggagatggagaccatcctggctaacacggtgaaaAAAAAAAAAAAAGTCCCAACAAAATA

Downstream sequence

AATATACTAATAAGTAAACAAATTTATGAGCTTCATTATTGTCTTTAAGTTTCTTGACAACAACCCACCAGGGCCTAGTCATGGAGAACAAATGCAACCT