Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017923
Fusion event
HBV-APOA2 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
471
Integrated sequence
GCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGT| |TTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCGTGTTGCTGT
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
End
161192897/161223107 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/1323028; hsa-mir-1182/Downstream/4079;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/20641, chr1-CpG: 54/Downstream/35580
Upstream sequence
TAGTCTCCTGTTCAACTGCCACTCTGCTAATCAACTTGGGCATCAGTTTTCCATAAGGCTTATGCACAGCTCTGTACTGCAGTTAAAAACTCTCTCTGTG
Downstream sequence
GACGGTGCTTAAAGTAAAAAACAACGAGTGGAAGCTCACAGTGGTGGCTTTTTCCAGAGAAGTCTGCAGGAAGGATTGTTTTCTTCTCTTGGGGAAGGGT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.