APOA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017924
Fusion event
HBV-APOA2 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
Polymerase;
Start
898
Integrated sequence
GTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTACTAAAACTAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTT| |GGGGTACCTTACCACAGGAACATATTGTACACAAAATCAAACAATGTTTTCGAAAAATTCCTATAAATAGACCTATTGATTGGAAAGTATGTCAACGAAT
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
161193156/161223366 (Hg38)
End
161193156/161223366 (Hg38)
Location type
Exonic
Target gene
APOA2
Nearest miRNA
hsa-mir-101-1/Upstream/1323287; hsa-mir-1182/Downstream/3820;
Nearest TSS
ENST00000473358/Upstream/8069; ENST00000465512/Downstream/42;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/20900, chr1-CpG: 54/Downstream/35321
Upstream sequence
AAGTCTGGACCCCACAGCTGGCTCTCCCACCCCTCAGCAAGCTCTCGCAGTTACCACATGATCCTTCGTGTTTCTTGCCTTCCATTTCCCTTGGGTGGAT
Downstream sequence
GGTTGGGTAGGTGGGGTTTCCTGGTTTGGGGTTTCTCAGACAAGGGCCCTCTAGGGAGGGTGCCCTGGACCCCCCACCACTCCTGGGCTGAGGAGCGTGT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate