VISDB Viral Integration Site DataBase

VIS ID

TVIS10017926

Fusion event

HBV-A2M integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

302

Integrated sequence

GCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTG| |GCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTT

Chromosome

chr12

Cytoband

p13.31

Reference genome

Start

End

9224964/9072368 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-98-5p

Nearest miRNA

hsa-mir-141/Upstream/2108177; hsa-let-7i/Downstream/167099;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/7249, chr12-CpG: 18/Downstream/167495

Upstream sequence

CTTTAAAACAAAGTCTAAACAGTTGCATTTTCTCTTTTCCCAAGTGAAAGATGTTTCTTTATACCTTCATTTTTTATGATTCTCATCTATTTGCATCACA

Downstream sequence

CACATGCTTAAATTGTAGCTGATTATAATTTTAGTTCAGATGTGTTTGAATCAATAGATTTATGTTCTGCTGATTTCAGTGCTCACCGTTGTATCCAGCT