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VISDB
Viral Integration Site DataBase
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TVIS10017928
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017928
Fusion event
HBV-GPR180 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1789
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCA| |TAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
95271908/94619654 (Hg38)
End
95271908/94619654 (Hg38)
Location type
Intronic
Target gene
GPR180
miRNAs that regulate target gene
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-103a-3p
;
hsa-mir-16-5p
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-548e-5p
;
hsa-mir-4328
;
hsa-mir-6838-5p
;
hsa-mir-4786-3p
;
hsa-mir-140-3p
;
hsa-mir-1972
;
hsa-mir-9-3p
;
hsa-mir-551b-5p
;
hsa-mir-4422
;
hsa-mir-6835-3p
;
hsa-mir-548c-3p
;
hsa-mir-4639-5p
;
hsa-mir-3157-5p
;
hsa-mir-5581-5p
;
hsa-mir-4297
;
hsa-mir-3605-5p
;
hsa-mir-3679-5p
;
hsa-mir-1185-5p
;
hsa-mir-3614-3p
;
hsa-mir-29a-5p
;
hsa-mir-6504-3p
;
hsa-mir-6757-3p
;
hsa-mir-496
;
hsa-mir-7977
;
hsa-mir-4446-5p
;
hsa-mir-4256
;
hsa-mir-103a-2-5p
;
hsa-mir-627-3p
Nearest miRNA
hsa-mir-1297/Upstream/2129434; hsa-mir-1267/Downstream/1807575;
Nearest TSS
ENST00000623511/Upstream/17751;
ENST00000438290/Downstream/83208;
Nearest CpG islands
None/Target,
chr13-CpG: 551/Upstream/17339
,
chr13-CpG: 73/Downstream/82281
Upstream sequence
TAGGCTTCTTTTGTGAAACTTGTTTCCTGCAGGTGATGGTTCATGACAATATCGACACCAGTGATTACTGTGCTTTCGGTACCTTCGCCCTCGGGGCCTT
Downstream sequence
CAGCGGAGGCATTTCCACCAATGAGCGAGTCATCAATGTTACCTTCTGTCCTACTGACCATCTGCATTAAGAAAAAGCAGTATAATTGCAAAAGACACAA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Sample Information
×
Sample name
74T
Sample type
Tumor
Gender
Female
CpG Island Information
×
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