VISDB Viral Integration Site DataBase

VIS ID

TVIS10017930

Fusion event

HBV-MYH10 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

3019

Integrated sequence

TTTCCCGGTCACCAGTTGGACCCTGCATTCGGAGCCAATTCAAACAATCCAGATTGGGACTTCAACCCCAACAAGGATCAATGGCCAGCGGCACACCAGG| |TAGGAGTGGGATCCTTCGGGCCAGGGTTCACTCCACCACACGGCAATCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATATTGACAACAGTACCAGCAGC

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

8385212/8481894 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1274a ; hsa-mir-106b-3p ; hsa-mir-92b-3p ; hsa-mir-505-3p ; hsa-mir-197-3p ; hsa-mir-26a-5p ; hsa-mir-23a-3p ; hsa-mir-200a-3p

Nearest miRNA

hsa-mir-1253/Upstream/294890; hsa-mir-10226/Downstream/3600005;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/4673, chr17-CpG: 188/Downstream/147792

Upstream sequence

TATCTGCTAATCAGCATAACACAAATGTAAGTGATCGTCAGAAAGaatcagacaggagcaatcagggtgttgcaagtcctgattacgcagagacgttaat

Downstream sequence

AGGAGGCAGGTGGGGGCCTCCGCAGGGGCTCAAGTGTTTGCAGAGCTGGGCCTCTAAGGTGGGCAAGGCCTCTTTCTTGAAGGGGACTGTGGCTCCACAG