Fusion event
HBV-MYH10 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;X protein;
Integrated sequence
GGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTC| |TGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAG
End
8385213/8481895 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1253/Upstream/294891; hsa-mir-10226/Downstream/3600004;
Upstream sequence
CGGAGGGGCGGTCATGGGGAGGAAAGGGGAGCTAAGCTGCTGGGTCGGGTCTGAGCAGCACCCCAAGACTGGAGCCCGAGGCAAGGAGGCTCACGGGAGC
Downstream sequence
GGAGGCAGGTGGGGGCCTCCGCAGGGGCTCAAGTGTTTGCAGAGCTGGGCCTCTAAGGTGGGCAAGGCCTCTTTCTTGAAGGGGACTGTGGCTCCACAGG
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.