VISDB Viral Integration Site DataBase

VIS ID

TVIS10017932

Fusion event

HBV-PCYT2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

Polymerase;

Start

898

Integrated sequence

GTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTACTAAAACTAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTT| |GGGGTACCTTACCACAGGAACATATTGTACACAAAATCAAACAATGTTTTCGAAAAATTCCTATAAATAGACCTATTGATTGGAAAGTATGTCAACGAAT

Chromosome

chr17

Cytoband

q25.3

Reference genome

Start

End

79862445/81904569 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-let-7b-5p ; hsa-mir-4632-3p ; hsa-mir-4707-3p ; hsa-mir-3130-3p ; hsa-mir-1292-3p ; hsa-mir-7108-3p ; hsa-mir-8072 ; hsa-mir-4786-5p ; hsa-mir-3960 ; hsa-mir-4285 ; hsa-mir-4673 ; hsa-mir-4742-5p ; hsa-mir-4645-5p ; hsa-mir-1911-3p ; hsa-mir-566 ; hsa-mir-6789-3p ; hsa-mir-4726-3p

Nearest miRNA

hsa-mir-10226/Upstream/210700; hsa-mir-4525/Downstream/332099;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/1482, chr17-CpG: 142/Downstream/6242

Upstream sequence

TGTGAGCTCCCCTTCAAATCTTTCCCACACCCAATGCATTTATAAGGCCTCTCTCTCACCTTGTATGGATTCTCTGATGTTCTGTAAGGACTGAGTTCTg

Downstream sequence

TGCGTTTCAGGCTGCAGGTGCCGTCTGCCCGTCTCACTTCCGGCCTCTCCACTGTGCTGGACACCCTCTCTGAGCAGCTTTGCTGGAAAGAGCGGAGAGC