VISDB Viral Integration Site DataBase

VIS ID

TVIS10017934

Fusion event

HBV-U2AF2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1730

Integrated sequence

ACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGAC| |TGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCT

Chromosome

chr19

Cytoband

q13.42

Reference genome

Start

End

56185749/55674383 (Hg38)

Location type

3UTR

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-455-3p ; hsa-mir-671-5p ; hsa-mir-542-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-324-3p ; hsa-mir-210-3p ; hsa-mir-196a-5p ; hsa-mir-92a-3p ; hsa-mir-588 ; hsa-mir-548s ; hsa-mir-3163 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-4701-5p ; hsa-mir-423-5p ; hsa-mir-486-3p ; hsa-mir-3184-5p ; hsa-mir-4688 ; hsa-mir-3064-3p ; hsa-mir-6743-5p ; hsa-mir-4698 ; hsa-mir-6721-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6888-5p ; hsa-mir-4529-5p ; hsa-mir-8063 ; hsa-mir-1226-5p ; hsa-mir-1252-5p ; hsa-mir-185-3p ; hsa-mir-3065-5p ; hsa-mir-3144-5p ; hsa-mir-3178 ; hsa-mir-3529-3p ; hsa-mir-3687 ; hsa-mir-4442 ; hsa-mir-4486 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-4508 ; hsa-mir-4721 ; hsa-mir-4743-5p ; hsa-mir-4751 ; hsa-mir-5001-5p ; hsa-mir-5787 ; hsa-mir-6089 ; hsa-mir-6758-5p ; hsa-mir-6762-5p ; hsa-mir-6781-5p ; hsa-mir-6845-5p ; hsa-mir-6856-5p ; hsa-mir-762

Nearest miRNA

hsa-let-7e/Upstream/286141; hsa-mir-10394/Downstream/2660305;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/8831, chr19-CpG: 91/Downstream/359

Upstream sequence

cagagtttgcagtgagctgagatcatgccattgcattccagcctgagcgaccgactgagcgagactccatctcaaaaaacaaacaaaaagaaaaaaagaa

Downstream sequence

AACAGCCTCTCCTTCTCCCATAGACCCCTTTCTTCTCCCCTTCCCCACGGTAGGAACATAGCGTGTTTATATTTTATGGCCAAACTATTTTGAATTTTGT