VISDB Viral Integration Site DataBase

VIS ID

TVIS10017935

Fusion event

HBV-BHLHE40 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

423

Integrated sequence

CCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATG| |CCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACC

Chromosome

chr3

Cytoband

p26.1

Reference genome

Start

End

5025011/4983326 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-941 ; hsa-mir-454-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-767-3p ; hsa-mir-374a-5p ; hsa-mir-345-3p ; hsa-mir-3140-5p ; hsa-mir-3620-3p ; hsa-mir-4686 ; hsa-mir-5187-3p ; hsa-mir-6828-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6749-3p ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-4469 ; hsa-mir-6784-5p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-7113-5p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-483-3p ; hsa-mir-4643

Nearest miRNA

hsa-let-7g/Downstream/266851;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/44, chr3-CpG: 43/Downstream/3398

Upstream sequence

TATATGCATTTAATTGTAATAATGTTCATTAATGGCTTCAAAAATTATTGTGTCCATAATTAATTAGCTACAGTTGAAAACATTTAAAGCCTACTAAAAC

Downstream sequence

ATGCAGCTTTCGGATGATGAAGGCCATTTCACTAGCAGTGACCTGATCAGCTCCCCGTTCCTGGGCCCACACCCACACCAGCCTCCTTTCTGCCTGCCCT