VISDB Viral Integration Site DataBase

VIS ID

TVIS10017936

Fusion event

HBV-SYNPR integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

3019

Integrated sequence

TTTCCCGGTCACCAGTTGGACCCTGCATTCGGAGCCAATTCAAACAATCCAGATTGGGACTTCAACCCCAACAAGGATCAATGGCCAGCGGCACACCAGG| |TAGGAGTGGGATCCTTCGGGCCAGGGTTCACTCCACCACACGGCAATCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATATTGACAACAGTACCAGCAGC

Chromosome

chr3

Cytoband

p14.2

Reference genome

Start

End

63378841/63393165 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-let-7a-5p

Nearest miRNA

hsa-let-7g/Upstream/2775295; hsa-mir-12124/Downstream/3832299;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/114636, chr3-CpG: 152/Downstream/470205

Upstream sequence

TTTCTGAACTTTATAATGATATCTCACCATTTCTTTGCCTGTCATTAATGTTTAAATGGAAAAGGGAAAGAATGCTTATAAGTTTGGCTGGGGAGGAAAG

Downstream sequence

cagaatcaaacacaccaaaacttattttctctcttcccccaatgatgaatatctaagatattttacttttttcctgtattacaaataaggcttaaaaaac