Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017937
Fusion event
HBV-AHSG integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
422
Integrated sequence
ACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTAT| |GCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGAC
Host Sequence
Chromosome
chr3
Cytoband
q27.3
Reference genome
End
186338722/186620933 (Hg38)
Location type
3UTR
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7g/Upstream/853029; hsa-mir-1248/Downstream/165739;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/50084, chr3-CpG: 20/Downstream/151880
Upstream sequence
TTTCTGAACTTTATAATGATATCTCACCATTTCTTTGCCTGTCATTAATGTTTAAATGGAAAAGGGAAAGAATGCTTATAAGTTTGGCTGGGGAGGAAAG
Downstream sequence
AGACATGGCAGAGATGAGGAGGTTTGGCACAGAAAACATAGCCACCATTTTGTCCAAGCCTGGGCATGGGTGGGGGGCCTTGTCTGCTGGCCACGCAAGT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.