Fusion event
HBV-ATP13A4 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
TCTGGGATTCTTTCCCGGTCACCAGTTGGACCCTGCATTCGGAGCCAATTCAAACAATCCAGATTGGGACTTCAACCCCAACAAGGATCAATGGCCAGCG| |GCACACCAGGTAGGAGTGGGATCCTTCGGGCCAGGGTTCACTCCACCACACGGCAATCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATATTGACAACAG
End
193247712/193529923 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/3699914; hsa-mir-3137/Downstream/1604583;
Upstream sequence
AATAAGTCACATAGACTGAGTTTTAATCTCCAGCATTGGATCTTAGACAGGAAACTAAAGTTCTCTAGGTCTGTGTTCTCTGAAAAGTGGGACAAGTACA
Downstream sequence
TAGGTAAATGCATAAGTCTGTTTGAAGTGGGAAGGGACCCATATCTTAAGATTCCTATAAGCATTCCAGGGCCACCCATGGCACCCCAGTTGGGTTGTTC
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.