COX7A2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017947
Fusion event
HBV-COX7A2 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
NA
Start
3350
Integrated sequence
| |
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
75950956/75241240 (Hg38)
End
75950956/75241240 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA6D
Target gene
COX7A2
miRNAs that regulate target gene
hsa-mir-548b-3p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10398/Upstream/2273487; hsa-mir-10524/Downstream/187167;
Nearest TSS
ENST00000381078/Upstream/35189; ENST00000607221/Downstream/2545;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/34569, chr6-CpG: 63/Downstream/43047
Upstream sequence
TACCTAGTTTTGTGCAGTAAGACCCAGAGCCAACCCTGCTTTGGAAGGTGTTTGTCTAACGTTCTTTGAGTAAGGAATGCTTCCTCACAATACCACAGAG
Downstream sequence
TCCTCTGCCCAATCTGACGAAGAGCCTAAAATGAAAATATTATTAAATAGACttagagcctaaagaaaccttcaaaaccaactattttcagtcgttcata
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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