GRHPR _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017949
Fusion event
HBV-GRHPR integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
pre-S1/pre-S2/S;Polymerase;
Start
694
Integrated sequence
CACTTGTATTCCCATCCCATCATCTTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTT| |CAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAATCCCTTTTTAC
Host Sequence
Chromosome
chr9
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
37432099/37432102 (Hg38)
End
37432099/37432102 (Hg38)
Location type
Exonic
Target gene
GRHPR
miRNAs that regulate target gene
hsa-mir-1180-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-101-2/Upstream/538571; hsa-let-7a-1/Downstream/3496908;
Nearest TSS
ENST00000422679/Upstream/15; ENST00000442009/Downstream/33297;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/9184, chr9-CpG: 129/Downstream/32715
Upstream sequence
GAGCCGCCCTGTGCCTCATGCGGCGACCGAGGCGCCCTCGGGAGACGGGCCCTGTCGGGTGTCGAGACGCGAACACGACCCAATGCCAAGAACGGGCGGT
Downstream sequence
GCTGTCAGTACCTTCCGAAAGCTGTGAGTCCCAGAGCAGCCCTGCACCCTAACCCCAACCCTCCTCTCAGCCCCCGGACTTCAGCCCTGCTCTGGCCCCT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate