Fusion event
HBV-PLS3 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
TCAAACAATGTTTTCGAAAAATTCCTATAAATAGACCTATTGATTGGAAAGTATGTCAACGAATTGTGGGGCTTCTGGGCTTTGCCGCTCCCTTTACACA| |ATGTGGTTACCCAGCATTAATGCCTTTGTATGCATGTATACAAGCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATAT
End
114869286/115634974 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7f-2/Upstream/811410; hsa-mir-105-1/Downstream/2751420;
Upstream sequence
attacaggggtgagccaccgtgcccaaccTCACTTGCTTCTTATCCTTACACTCCCCCAGCCCCAGAGAAACTGCCACATACACCACAAAAACCAAACAT
Downstream sequence
TGGTTTTGGGACTGCTTTGGCAGATCATTAAGATCGGTTTGTTCGCTGACATTGAATTAAGCAGGAATGAAGGTAATGGAACACAGTCATTCTGGCAGTT
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.