Basic Information
VIS ID
TVIS10017955
Fusion event
HBV-chr13 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1056
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
96229483/95577229 (Hg38)
End
96229485/95577231 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
CLDN10 ; DZIP1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-124-3p ; hsa-mir-99b-3p ; hsa-let-7e-5p ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6729-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-3925-5p ; hsa-mir-486-5p
Nearest miRNA
hsa-mir-1297/Upstream/3087009; hsa-mir-1267/Downstream/849998;
Nearest TSS
ENST00000623511/Upstream/17079; ENST00000376795/Downstream/10443;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/23987, chr13-CpG: 89/Downstream/64121
Upstream sequence
CACTCGCTATCTGCTTTTTTTTTATTTCTTGTCATAGTATAAATTTTCTGTCGAAAATTGTTTAGAAATCAGCTTGACTGAGAACAGGATTACAGTTTAA
Downstream sequence
TATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAA
Target sequence
GG
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
Curate