Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018001
Fusion event
HBV-POU2F3 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
781
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
End
120165340/120294631 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-3620-5p ; hsa-mir-1587 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6829-5p ; hsa-mir-4656 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-6081 ; hsa-mir-3135b ; hsa-mir-661 ; hsa-mir-378g ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-3679-3p ; hsa-mir-5681b ; hsa-mir-6832-3p ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-1273g-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4755-3p ; hsa-mir-342-3p ; hsa-mir-1972 ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-1228-3p ; hsa-mir-5694 ; hsa-mir-3675-3p ; hsa-mir-4293 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4684-5p ; hsa-mir-4768-3p ; hsa-mir-548c-3p ; hsa-mir-6771-3p
Nearest miRNA
hsa-mir-10392/Upstream/981619; hsa-let-7a-2/Downstream/1805126;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/54452, chr11-CpG: 68/Downstream/30465
Nearest cancer related gene
POU2F3(TSG, No orient, 0)
Upstream sequence
GCCAAACACACGACGTGAAATGCTGAGATCTCCATCAACAGGTGACCGCCGAATTCACGACGATCCAACGTAACCGTGGAAGCTGATGGAAAAAAGGAGG
Downstream sequence
GCAATCTTCTAAGGGGACTTCCTCAGAGGTCATTAAATGCATTGAAAACTGGTTCTGGTCCTCGACCCTAAGCTGCTGGAGGAGGGGGTGTGGGAGCAGA
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13