VISDB Viral Integration Site DataBase

VIS ID

TVIS10018004

Fusion event

HBV-TERT integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

459

Chromosome

chr5

Cytoband

p15.33

Reference genome

Start

End

1272399/1272284 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-138-5p ; hsa-mir-498 ; hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-512-5p ; hsa-mir-1207-5p ; hsa-mir-1266-5p ; hsa-mir-1182 ; hsa-mir-181a-5p ; hsa-mir-6776-3p ; hsa-mir-197-3p ; hsa-mir-6740-3p ; hsa-mir-6760-3p ; hsa-mir-532-5p ; hsa-mir-3064-5p ; hsa-mir-422a ; hsa-mir-346 ; hsa-mir-1226-3p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-143-3p ; hsa-mir-3161 ; hsa-mir-3605-5p ; hsa-mir-3620-3p ; hsa-mir-3682-3p ; hsa-mir-4323 ; hsa-mir-4712-3p ; hsa-mir-4733-3p ; hsa-mir-4758-3p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-7112-3p

Nearest miRNA

hsa-mir-4635/Upstream/205658; hsa-mir-10397/Downstream/37026;

Nearest TSS

Nearest CpG islands

chr5-CpG: 26/Target, None/Upstream, None/Downstream

Nearest cancer related gene

TERT(OG, No orient, 0)

Upstream sequence

tttcaaccattatcattttacatatgctttctgactctttttcactaccttcttcttaaatttctatcatgtgcatgttagttctgttgatggtgtccca

Downstream sequence

CGGCAGAGGAGAGGGCATGAGCCACAAATGTGGCCTGCCCCGGCCAGAGCTGGGCACTTGTTTCTTCCGATCAGGACGTGTGGACCTGCGGCCAAGCCCG

Target sequence

CCTGGGGCGGGAAGACACAGGTGAGAGACGGGCAGGGCATGTGCTGGACATGCGTACACTCAAACCGAGCCACACACAGACACAGAACCTCATACACACAAACGACACGTCTACCATTCAGCCGGCAAACACCTCAGAAACATACCAGATGAGACCTCTGAACAAACAATCCCTGCTCCCCACTCTCACCATGCACTGGGGCGGCTGAAACAGATCCAGCCACAGGTGTGACCACATCCTTGCTCTGAATCATCA