APOL2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018046
Fusion event
HBV-APOL2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
454
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
36633639/36237593 (Hg38)
End
36633642/36237596 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
APOL2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-221-3p ; hsa-mir-34a-5p ; hsa-mir-1273e ; hsa-mir-4302 ; hsa-mir-6733-3p ; hsa-mir-5094 ; hsa-mir-5694 ; hsa-mir-383-5p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4755-3p
Nearest miRNA
hsa-mir-1286/Upstream/900794; hsa-let-7a-3/Downstream/49251;
Nearest TSS
ENST00000624155/Upstream/32753; ENST00000475519/Downstream/1631;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/171230, chr22-CpG: 24/Downstream/84809
Upstream sequence
gagcccctgggctcaagtgatccttctgcctcagccttccaggtagctgggactacaggcacacggcaccatgcaggactaatttgttaatttttcattt
Downstream sequence
agagacagcatctcctgtgttgcccaagctgtcttgagctcctagcatcatgtgattctcccgcctctgcctcccacagcactgaattacaggcctcagc
Target sequence
cag
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
Curate