Basic Information
VIS ID
TVIS10018143
Fusion event
HBV-chr17 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1725
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
37007198/38850945 (Hg38)
End
37007198/38850945 (Hg38)
Location type
Intronic
Target gene
RPL23 ; SNORA21
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-615-3p ; hsa-mir-503-5p ; hsa-mir-183-5p ; hsa-mir-3200-3p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6872-3p ; hsa-mir-3934-5p ; hsa-mir-6504-3p ; hsa-mir-552-3p ; hsa-mir-1228-3p ; hsa-mir-1285-3p ; hsa-mir-25-3p ; hsa-mir-3187-5p ; hsa-mir-32-5p ; hsa-mir-335-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4325 ; hsa-mir-508-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-6860 ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-939-3p
Nearest miRNA
hsa-mir-1180/Upstream/25053; hsa-mir-10226/Downstream/64034;
Nearest TSS
ENST00000595228/Upstream/284; ENST00000584106/Downstream/2479;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/9537, chr17-CpG: 46/Downstream/2273
Nearest cancer related gene
RPL23(OG, No orient, 0)
Upstream sequence
TTTTGCAAAAGGATATGACATTTTGTTTGAAACATAGTCACCTAGTTTACAGACTTGAATTCTGCACATTTTCTTAGCACAGGAATTAATTTCTTAAGAA
Downstream sequence
CTGGCAATGAGCAGAGACCAAGCTATTCAGATTTACACTGGAAAACAGTTTGAATTCCTGGGCCCAAGCACCAGGCTTTGTTTTACTTTTAATGAACTGT
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
Curate