FHIT _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018194
Fusion event
HBV-FHIT integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1204
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
60163954/60178226 (Hg38)
End
60163954/60178226 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
FHIT
miRNAs that regulate target gene
hsa-mir-143-3p ; hsa-mir-217 ; hsa-mir-331-3p ; hsa-mir-625-5p
Nearest miRNA
hsa-let-7g/Upstream/4325632; hsa-mir-12124/Downstream/439579;
Nearest TSS
ENST00000440867/Upstream/97386; ENST00000475527/Downstream/1073158;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1128008, chr3-CpG: 48/Downstream/1072706
Nearest cancer related gene
FHIT(TSG, No orient, 0)
Upstream sequence
cacttgcacttgggaggcggaggtttcagtgagccaagattgcgccactgaactgcagtctgggtgacacagggagactgtgtctcagaaacaaacaaaa
Downstream sequence
TCTTTTTATTTCACAAATGTTAACTTCCCAAATGGGTTAGCAAGGGAAAACTATCATTATTATAAAGAAGCGCAGATAAGGcagacacaatggctcacac
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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