NFE2L2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018227
Fusion event
HBV-NFE2L2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
2561
Host Sequence
Chromosome
chr2
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
178127822/177263094 (Hg38)
End
178127842/177263114 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
NFE2L2
miRNAs that regulate target gene
hsa-mir-144-3p ; hsa-mir-153-3p ; hsa-mir-142-5p ; hsa-mir-27a-3p ; hsa-mir-26b-5p ; hsa-mir-106b-3p ; hsa-mir-374a-5p ; hsa-mir-27b-3p ; hsa-mir-132-5p
Nearest miRNA
hsa-mir-10b/Upstream/7084; hsa-mir-1244-1/Downstream/50692;
Nearest TSS
ENST00000437798/Upstream/30607; ENST00000428541/Downstream/340;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/49607, chr2-CpG: 162/Downstream/431
Nearest cancer related gene
NFE2L2(OG, No orient, 0)
Upstream sequence
CTACCTGGGCTTCTGCATCTGCTCCTCCTTGAGCCGCTGCTCCCACAACATGCGATGTTCTGGCTTAAGCCGAACAGCTTCCTTCTTCGTTCTTGTTGAA
Downstream sequence
AAAGAAGTTAGAAATATAAATATCTACTTTTAAAGTTTCTACAAAGGATGAGCAGAAACTTCTTTTCACTTTTATAACAATTCACAGAAATTAGCAAGTG
Target sequence
TTTCCTAAAATTCATTTACA
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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