VISDB Viral Integration Site DataBase

VIS ID

TVIS10018233

Fusion event

HBV-chr11 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

1729

Chromosome

chr11

Cytoband

q13.3

Reference genome

Start

End

69466861/69652093 (Hg38)

Location type

Intronic

Fragile sites / regions

FRA11H ; FRA11A

Target gene

CCND1 ; LTO1

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-195-5p ; hsa-mir-193b-3p ; hsa-mir-424-5p ; hsa-mir-16-1-3p ; hsa-mir-34a-5p ; hsa-mir-503-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-let-7b-5p ; hsa-mir-19a-3p ; hsa-mir-302a-3p ; hsa-mir-15b-5p ; hsa-mir-449a ; hsa-mir-17-5p ; hsa-mir-302c-3p ; hsa-mir-106b-5p ; hsa-let-7e-5p ; hsa-mir-365a-3p ; hsa-mir-19b-1-5p ; hsa-mir-520b ; hsa-mir-34b-3p ; hsa-mir-338-3p ; hsa-mir-9-5p ; hsa-mir-374b-5p ; hsa-mir-425-5p ; hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-183-5p ; hsa-mir-93-5p ; hsa-mir-26b-5p ; hsa-let-7f-5p ; hsa-mir-92b-3p ; hsa-mir-196a-5p ; hsa-mir-92a-3p ; hsa-mir-138-5p ; hsa-mir-106a-5p ; hsa-mir-27a-3p ; hsa-mir-383-5p ; hsa-mir-490-3p ; hsa-mir-603 ; hsa-mir-142-5p ; hsa-mir-340-5p ; hsa-mir-448 ; hsa-mir-548k ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-3973 ; hsa-mir-5590-3p ; hsa-mir-548av-5p ; hsa-mir-8054 ; hsa-mir-6077 ; hsa-mir-214-5p ; hsa-mir-558 ; hsa-mir-1234-3p ; hsa-mir-4524a-5p ; hsa-mir-4694-3p ; hsa-mir-4524b-5p ; hsa-mir-1199-3p ; hsa-mir-6735-3p ; hsa-mir-6748-3p ; hsa-mir-6874-5p ; hsa-mir-7107-5p ; hsa-mir-497-5p ; hsa-mir-545-3p ; hsa-mir-4311 ; hsa-mir-4672 ; hsa-mir-6838-5p ; hsa-mir-8066 ; hsa-mir-3157-5p ; hsa-mir-4691-3p ; hsa-mir-758-5p ; hsa-mir-374a-5p ; hsa-mir-4708-5p ; hsa-mir-4756-3p ; hsa-mir-193a-3p ; hsa-mir-4691-5p ; hsa-mir-6792-3p ; hsa-mir-655-5p ; hsa-mir-4709-3p ; hsa-mir-20b-5p ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-491-3p ; hsa-mir-216b-3p ; hsa-mir-6500-3p ; hsa-mir-593-3p ; hsa-mir-204-3p ; hsa-mir-494-3p ; hsa-mir-4261 ; hsa-mir-4646-5p ; hsa-mir-4666a-5p ; hsa-mir-4781-3p ; hsa-mir-708-5p ; hsa-mir-29a-3p ; hsa-mir-24-3p ; hsa-mir-152-3p ; hsa-mir-206 ; hsa-mir-3907 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-7706 ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-1299 ; hsa-mir-563 ; hsa-mir-380-5p ; hsa-mir-1193 ; hsa-mir-8069 ; hsa-mir-4537 ; hsa-mir-202-3p ; hsa-mir-2392 ; hsa-let-7c-5p ; hsa-let-7g-5p ; hsa-let-7a-5p ; hsa-let-7d-5p ; hsa-mir-4500 ; hsa-mir-98-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3191-5p ; hsa-mir-513a-5p ; hsa-mir-7112-3p ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-1253 ; hsa-mir-3663-5p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-7845-5p ; hsa-mir-518c-5p ; hsa-mir-9500 ; hsa-mir-6873-5p ; hsa-mir-5197-3p ; hsa-mir-95-3p ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-574-5p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-5087 ; hsa-mir-298 ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-593-5p ; hsa-mir-145-3p ; hsa-mir-676-5p ; hsa-mir-5009-3p ; hsa-mir-4715-5p ; hsa-mir-541-5p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-556-5p ; hsa-mir-4796-3p ; hsa-mir-891b ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-944 ; hsa-mir-1257 ; hsa-mir-323b-3p ; hsa-mir-646 ; hsa-mir-6768-5p ; hsa-mir-4746-3p ; hsa-mir-3648 ; hsa-mir-875-3p ; hsa-mir-4797-5p ; hsa-mir-466 ; hsa-mir-3941 ; hsa-mir-4643 ; hsa-mir-4735-3p ; hsa-mir-4789-3p ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-3189-5p ; hsa-mir-4758-3p ; hsa-mir-5699-5p ; hsa-mir-1915-5p ; hsa-mir-6884-3p ; hsa-mir-3922-5p ; hsa-mir-2861 ; hsa-mir-34a-3p ; hsa-mir-3940-5p ; hsa-mir-34c-5p ; hsa-mir-101-3p ; hsa-mir-146a-5p ; hsa-mir-576-3p ; hsa-mir-211-5p ; hsa-let-7a-3p ; hsa-mir-892b ; hsa-mir-1243 ; hsa-mir-1273f ; hsa-mir-1276 ; hsa-mir-1293 ; hsa-mir-224-5p ; hsa-mir-3147 ; hsa-mir-3148 ; hsa-mir-3153 ; hsa-mir-3170 ; hsa-mir-3179 ; hsa-mir-3202 ; hsa-mir-323a-5p ; hsa-mir-342-5p ; hsa-mir-3919 ; hsa-mir-432-3p ; hsa-mir-4425 ; hsa-mir-4483 ; hsa-mir-4533 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-4716-3p ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-5572 ; hsa-mir-5587-5p ; hsa-mir-608 ; hsa-mir-625-5p ; hsa-mir-651-3p ; hsa-mir-653-3p ; hsa-mir-668-3p ; hsa-mir-6733-5p ; hsa-mir-6737-5p ; hsa-mir-6739-5p ; hsa-mir-6747-5p ; hsa-mir-6794-5p ; hsa-mir-6812-5p ; hsa-mir-6819-5p ; hsa-mir-6855-5p ; hsa-mir-6885-3p ; hsa-mir-8068 ; hsa-mir-8080 ; hsa-mir-876-3p ; hsa-mir-3135a ; hsa-mir-4666a-3p ; hsa-mir-4803

Nearest miRNA

hsa-mir-10392/Upstream/568761; hsa-let-7a-2/Downstream/631862;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/5409, chr11-CpG: 25/Downstream/1949

Nearest cancer related gene

CCND1(OG, No orient, 0)

Upstream sequence

AAAGCAATGTGGCAAAGAAATGTTTGCCTTAGTTTTCTGACATATAAAATAGACCCAAGCAATTCCATGACACGTTCAAGAGAATATCTTCTTGTGGCAA

Downstream sequence

TCCTACGATACGCTACTATAAAGAGAAGACGAAATAGTGACATAATATATTCTATTTTTATACTCTTCCTATTTTTGTAGTGACCTGTTTATGAGATGCT

Target sequence

GTGACAAACCATCCAGTGGAGGTTTGTCGGGCACCAGCCAGCGTAGCAGGGTCGGGAAAGGCCACCTGTCCCAC