Basic Information
VIS ID
TVIS10018262
Fusion event
HBV-chr16 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1823
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
70196261/70162358 (Hg38)
End
70196261/70162358 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
CLEC18C ; PDPR
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-18a-3p ; hsa-mir-544a ; hsa-mir-3907 ; hsa-mir-7106-5p ; hsa-mir-1193 ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6894-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6132 ; hsa-mir-6836-5p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-1185-5p ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4756-5p ; hsa-mir-4270 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-2392
Nearest miRNA
hsa-mir-1225/Upstream/131936; hsa-mir-11401/Downstream/6706578;
Nearest TSS
ENST00000527434/Upstream/16554; ENST00000565806/Downstream/10964;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/47502, chr16-CpG: 69/Downstream/25689
Upstream sequence
CTCCGAGGAGCAGGGGCTGCACGCAGCTGGGCCGGGGCGGAGGCAGCAGTCGGGCCAGCAGGAGCGGGGAGGGGAGGCCATGGTTCCACTTCAGCATCGG
Downstream sequence
AGTGGGATCTTTTCTAGAGATCCTGGGTGACTTTGGGTGCACAGGGTGACCGAGCATTTCTGCCCCTGTGAATGTGGCACTAACACTGTGCACTGTCTCC
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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