VISDB Viral Integration Site DataBase

VIS ID

TVIS10018270

Fusion event

HBV-chr10 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

1737

Chromosome

chr10

Cytoband

p15.3

Reference genome

Start

End

1064800/1018860 (Hg38)

Location type

Intronic

Target gene

GTPBP4 ; IDI2 ; IDI2-AS1

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-26b-5p ; hsa-mir-92a-1-5p ; hsa-mir-16-5p ; hsa-mir-450a-2-3p ; hsa-mir-6763-5p ; hsa-mir-6857-5p ; hsa-mir-6810-5p ; hsa-mir-3150a-3p ; hsa-mir-2110 ; hsa-mir-6825-5p ; hsa-mir-526b-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-4683 ; hsa-mir-4693-3p ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-7161-3p ; hsa-mir-1264 ; hsa-mir-4715-3p ; hsa-mir-4727-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-6870-3p ; hsa-mir-1224-3p ; hsa-mir-6729-3p

Nearest miRNA

hsa-mir-5699/Upstream/376700; hsa-mir-107/Downstream/1057159;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/29803, chr10-CpG: 123/Downstream/29537

Nearest cancer related gene

GTPBP4(TSG, No orient, 0)

Upstream sequence

taggcatttcaaggatacaactaagcagtcacacgaagaaaagtggaaggaagggaaagcaataaaaacagacccacaTTagggaacgtttctcacctag

Downstream sequence

CACCAAAACTTAACATATAGTTTACTTTGTGTTAAACAACAACAGTATGTTTTAAAGCAAGTATGTCTTTATTTGTAAGCATATTACTGAAACGATCAAA

Target sequence

CACCAAAACTTAACATATAGTTTACTTTGTGTTAAACAACAACAGTATggccgggcgcggcagctcatgcctgtaatcccagcactttgggaggccgaggcaggcggatcacgaggtcaggagatcgagaccatcctggctaacacggtgaaaccccgtctctactaaaaatacaaaaaattagctgggtgtggtggcgggcgcctgtagtcccaactacttgggaggctgaggcaggagaatggcttgaacccg