Basic Information
VIS ID
TVIS10018306
Fusion event
HBV-chr12 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1839
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
49077286/48683503 (Hg38)
End
49077286/48683503 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
KANSL2 ; LOC144438
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-34a-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/28973; hsa-let-7i/Downstream/88472;
Nearest TSS
ENST00000382841/Upstream/1265; ENST00000548054/Downstream/12474;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/985, chr12-CpG: 66/Downstream/32769
Upstream sequence
ccaggaggggagctgccaaccacaagcggctgtcgagctcttgagatgtgtcagatgcaaccgaggaactgaattgctaattttatcccattttaattaa
Downstream sequence
ttttgatttcaatagccatgcgtggctCTGCTGTGCTGAGCTAAAGGGCTATAATCTCCCATCTGGACAAAAGCTCTCCCTGGACAAAAGTCCCCAGAAG
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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