Basic Information
VIS ID
TVIS10018316
Fusion event
HBV-chr3 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28622513
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
3538
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
184086708/184368920 (Hg38)
End
184086708/184368920 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
POLR2H ; THPO
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-let-7b-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-let-7g/Upstream/127431; hsa-mir-1248/Downstream/884290;
Nearest TSS
ENST00000440867/Upstream/2405; ENST00000496527/Downstream/4517;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/5422, chr3-CpG: 104/Downstream/10985
Upstream sequence
ACCACGAGAGGCTCAAGTGTGATGAGTGGAGTGTTAACAGTGTAGGGAAAATAGAGTGTGTATCAGCAGAGACCACCGAAGACTGCATCGCCAAGATCAT
Downstream sequence
CATTATTTTTATGGAAGCTTTGGGTAGAGGCTTTTAGCTACAGGCATGGGAGATGACTATGAAGAGAGTAGGACGAGAGGACTTGGTGGTTCTGGAAGCA
Reference
Cancer Genome Atlas Research Network. Electronic address, w. b. e. and N. Cancer Genome Atlas Research . Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. Cell ,2017,169(7): 1327-1341 e13
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