Basic Information
VIS ID
TVIS10018387
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
499
End
598
Integrated sequence
CAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCAC
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37.55
Start
51476452/51010780 (Hg38)
End
51476470/51010798 (Hg38)
Fragile sites / regions
FRA1B
Nearest miRNA
hsa-mir-12136/Upstream/6465228; hsa-mir-101-1/Downstream/49039;
Nearest TSS
ENST00000473358/Upstream/40836; ENST00000474016/Downstream/91436;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/32416, chr1-CpG: 87/Downstream/225297
Nearby gene
CDKN2C
Nearest cancer related gene
CDKN2C(TSG, No orient)
Upstream sequence
tgatgcctggtcTAGATAAGAGGTTTTAAATGGAGAAATTAGAGCACTTCTAGGGAGAGGAGCAAACTCAAGTCTTTTATTGTGGGAAAGGGGGAAACAC
Downstream sequence
agaaaaacaacagtaataaaagacatgcaggacagattcaaatcgcctaacatatatataattggaattttgaatgcagaagagaaagagaatggggctg
Target sequence
agaaagaaagaaagaata
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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