VISDB Viral Integration Site DataBase

VIS ID

TVIS10018388

Fusion event

HBV-ABL2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

371

End

470

Integrated sequence

TCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCC

Chromosome

chr1

Cytoband

q25.2

Reference genome

Start

End

179069801/179100666 (Hg38)

Location type

Exon1

Target gene

miRNAs that regulate target gene

hsa-mir-140-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-92a-3p ; hsa-mir-20a-5p ; hsa-mir-4755-5p ; hsa-mir-5006-3p ; hsa-mir-6829-3p ; hsa-mir-6874-5p ; hsa-mir-6791-3p ; hsa-mir-3121-5p ; hsa-mir-4761-5p ; hsa-mir-3908 ; hsa-mir-6507-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-139-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-548e-5p ; hsa-mir-107 ; hsa-mir-6081 ; hsa-mir-2861 ; hsa-mir-939-3p ; hsa-mir-7851-3p ; hsa-mir-649 ; hsa-mir-490-3p ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-6879-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-6773-3p ; hsa-mir-5693 ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-500b-3p ; hsa-mir-4279 ; hsa-mir-2355-5p ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-122-3p ; hsa-mir-4446-5p ; hsa-mir-642a-5p ; hsa-mir-6826-3p ; hsa-mir-570-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3663-5p ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-660-3p ; hsa-mir-526b-5p ; hsa-mir-6868-3p ; hsa-mir-6861-3p ; hsa-mir-4751 ; hsa-mir-6870-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-125a-5p ; hsa-mir-26a-1-3p ; hsa-mir-188-3p ; hsa-mir-605-5p ; hsa-mir-7849-3p ; hsa-mir-8485 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-3672 ; hsa-mir-4294 ; hsa-mir-6864-3p ; hsa-mir-8055

Nearest miRNA

hsa-mir-101-1/Upstream/422751; hsa-mir-1182/Downstream/703258;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/17772, chr1-CpG: 73/Downstream/128362

Nearest cancer related gene

ABL2(OG, No orient, 0)

Upstream sequence

TGAATTTCACGTACACTACAATTATTCTCTCTCTAAACTAATATAAATGGTTAGTTATAGAGTTTACCCCCTAGGGCTCAGGGAGAAGACAAGGATAGCA

Downstream sequence

CTCAGTAGCCTGGAGTGACAGGTAGGACCCTGAAAATTTGCTGATGCGAGTACAGTGATGAACAAAGAACCTTCCAGAATAGACACAGATGACATGTATC

Target sequence

TGCTAGCATTCGACAGTTTGCCTCCAGCTTTTCTAAAAGGTTACTTAGCATGCTCGGAGACCTCAGCTTCTGAGGGTTCAG