MRPL47 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018389
Fusion event
HBV-MRPL47 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
910
End
1009
Integrated sequence
GCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTT
Host Sequence
Chromosome
chr3
Cytoband
q26.33
Reference genome
GRCh37.55
Start
179306766/179588978 (Hg38)
End
179306784/179588996 (Hg38)
Location type
Exon1
Target gene
MRPL47
miRNAs that regulate target gene
hsa-let-7b-5p
Nearest miRNA
hsa-let-7g/Upstream/3073827; hsa-mir-1224/Downstream/4297804;
Nearest TSS
ENST00000440867/Upstream/2490; ENST00000477177/Downstream/15644;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/25303, chr3-CpG: 34/Downstream/15562
Upstream sequence
GCAGAGAGAGGCCCAGAAGAGGCACCAGCGAAGAGACAAGAAGTTGTAGCCGGATCCCGCCTGGGCCCTCGGCTTGGAGGCTTCAGAGGTGTAGGTGGTC
Downstream sequence
TAGAATAAAAAAAGCGTAACAGCAATTTATACAAAAATATTTCCTTGTTATTCAATACTATCAAAATATGCATAAATCAATTACATCAAAGCTTCAAACA
Target sequence
GTTTCTCACGTTCCAGTC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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