VISDB Viral Integration Site DataBase

VIS ID

TVIS10018393

Fusion event

HBV-DDX55 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

851

End

950

Integrated sequence

AAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTA

Chromosome

chr12

Cytoband

q24.31

Reference genome

Start

End

124104508/123619961 (Hg38)

Location type

Intron13

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-455-3p ; hsa-mir-615-3p ; hsa-mir-1277-5p ; hsa-mir-493-5p ; hsa-mir-190a-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-27b-5p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-590-5p ; hsa-mir-21-5p ; hsa-mir-5580-3p ; hsa-mir-5583-3p ; hsa-mir-4517 ; hsa-mir-1276 ; hsa-mir-4796-5p ; hsa-mir-654-3p

Nearest miRNA

hsa-let-7i/Upstream/83190; hsa-mir-3612/Downstream/717220;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/17256, chr12-CpG: 43/Downstream/13589

Upstream sequence

CCACTCTTCTCTGCTGAATTCCAGGTTCAGGGGGAGGACTGGCCACAGTGAAGCATTTTGCTTCCTTTCTTCCCCTGAAACTTAGTACTATATGATCCTG

Downstream sequence

AGGGTTCTGATATTGAAGATGAGGACATGGAAGAACTTCTTAATGACACAAGACTCTTGAAAAAACTTAAGAAAGGCAAAATAACTGAAGAAGAATTTGA

Target sequence

GTAAAGTTTACTTTTACTTACATTAACTTAGAATCTTGAACAAATTTATTGTAGTAGTTCTTTAAATAGGAATTGTGTGGGGCTGTCAGATTTCTGTTACGTTGGCGACCAGGGTGGGGAATTTGCTCTATTTGCAGAAGCCAATCTGAGAGCTTATAGTTCTTGAGTTAAAACTGCTGGTTTCACTACAACACTATTGCTGAAAAATTTAGTAGTTTATTGGTTTCTTCTGCACTT