Basic Information
VIS ID
TVIS10018394
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
447
Integrated sequence
TTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTT| |CTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAA
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37.55
Start
112782887/112128573 (Hg38)
End
112782894/112128580 (Hg38)
Nearest miRNA
hsa-mir-1267/Upstream/1787544; hsa-mir-4502/Downstream/1134340;
Nearest TSS
ENST00000623511/Upstream/21454; ENST00000561786/Downstream/68770;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/21774, chr13-CpG: 112/Downstream/34922
Nearby gene
SOX1-OT
Upstream sequence
TCTTCATTTACAAAATCAGCTTCTTCCTTACTAGTGCTTGATCAGATCTGTTAATTGGTTGCAAATGCCCTTGTCTTTTCTTCCTTCCCACCTGCTGTAA
Downstream sequence
GAGCCTCAACGGTAAATCCTCTTACTGCCCATGGGGATGTGGTCCTCTAATTAATCGCTGTGCTAAGCCAGACCTTGAAGTCTTCAGCTGAGATCGAGAT
Target sequence
TCTCCAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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