SERPINF2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018395
Fusion event
HBV-SERPINF2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
444
End
543
Integrated sequence
CTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAG
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37.55
Start
1649685/1746391 (Hg38)
End
1649685/1746391 (Hg38)
Location type
Intron5
Target gene
SERPINF2
miRNAs that regulate target gene
hsa-mir-224-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-3191-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6832-3p ; hsa-mir-6892-3p ; hsa-mir-6887-3p ; hsa-mir-4687-5p
Nearest miRNA
hsa-mir-22/Upstream/32404; hsa-mir-10226/Downstream/303517;
Nearest TSS
ENST00000595228/Upstream/3365; ENST00000571149/Downstream/15568;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/12193, chr17-CpG: 18/Downstream/7762
Upstream sequence
tacacctccctaccatgttgacatcaagcttagccatgtaactgttttgccaaggaaatgtagacagaagacacatacatcattttcaagaagaagccta
Downstream sequence
gccggggaatctgcttatttacaagtcctcctggtgattttttttttttttttgagacagagtcttgctctgtcacccaggctagagtgcagtggtgtga
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate