Basic Information
VIS ID
TVIS10018397
Fusion event
HBV-LINC01115 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1820
Integrated sequence
TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37.55
Start
842197/846255 (Hg38)
End
842204/846262 (Hg38)
Location type
Intron2
Target gene
LINC01115
Nearest miRNA
hsa-mir-10b/Downstream/5128400;
Nearest TSS
ENST00000437798/Upstream/103767; ENST00000452177/Downstream/21929;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/113159, chr2-CpG: 150/Downstream/21982
Upstream sequence
TACAAGATTACAGAACTGTACCTAATTCCTATTACTGTGTTTCAAAGAAACACGTTTTGTAAGGTTTTTAAAATAATTCTGATAAAATGTTAAGGTGTTC
Downstream sequence
CTCTATGCCAGGGTTGCTGCGTGGAGAGCGGGTGGAATATCTGAAACCAGAAGGAAAGGACACCTCAGTCTACTGCACACAGAGGCTCTAGGGCTCAGCC
Target sequence
GCAGTGG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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