VISDB Viral Integration Site DataBase

VIS ID

TVIS10018399

Fusion event

HBV-SUCLG2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

611

End

2942

Integrated sequence

CCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTAC

Chromosome

chr3

Cytoband

p14.1

Reference genome

Start

End

67571067/67520643 (Hg38)

Location type

Exon7

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-92a-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-3679-3p ; hsa-mir-2355-5p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-627-3p ; hsa-mir-6734-3p ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-6887-3p ; hsa-mir-3127-3p ; hsa-mir-6793-3p

Nearest miRNA

hsa-let-7g/Upstream/294953; hsa-mir-12124/Downstream/1528315;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/521631, chr3-CpG: 45/Downstream/133561

Upstream sequence

ATAAGCTCAGATCCATACGTTGTAACAAGGAGTTGGTGAAGCTGACCTCAGAAGTCCATGTACCTGGCTTCTCAGCCTCTTGGCCAGTTGCCCGCACTTT

Downstream sequence

TAGTGGGAAAGTCAAATTAATTCAGCATTAAGCTGATTTCTACTTGGAAATCTATACAAACTTGCTACACGAATCAAATGGCTTCATTTTCAGGCTCTTA

Target sequence

CCTTAAAAATGAGCTCCGGGTTTGAAGCAGCCACCTCTTCAATGTCGACGCCCCCCTGGGGGCTGCCCACCAGCACGGGGCCATTGCAGGACCGGTCCATCAGAATTGCCAGGTAGGTTTCTCTGGAAATATCCAAGGCTTCAGCAACCATCACCTACCACAT