Basic Information
VIS ID
TVIS10018402
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh37.55
Start
179744976/178823822 (Hg38)
End
179744976/178823822 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/4399958; hsa-mir-1305/Downstream/3345471;
Nearest TSS
ENST00000502981/Upstream/915886; ENST00000512480/Downstream/641483;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1381268, chr4-CpG: 160/Downstream/1234063
Nearby gene
LINC01098
Upstream sequence
AGGTATGTGTGAATATCCTCATGGTAGTCTGGTACTTCATTAACACTCACTGGCTTTTCATCTTCTAATATAATTGACATGTCCATAGTATGTGGTGACT
Downstream sequence
GTCAGCCCACAAAGTGACTTAACTCTTTGACTGATTAATCCTGTGTTCAGATTGTCTCTTTTTTCCCTTCCCCTATGAACTGCATAGTCTCTAGTGTGAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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